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Kamala Harris and second gentleman Doug Emhoff toured the Institut Pasteur in Paris on Tuesday to talk with scientists about global preparedness for pandemics in the vice president's third overseas trip since taking office.
Upon arriving at the institute on Monday afternoon Paris time, Harris and her husband met with a French virologist and immunologist James Philip Di Santo and an American researcher.
Di Santo said they were working on understanding why people have differing symptoms and outcomes from the coronavirus and were relying heavily on nasal swabs in their research.
Harris joked she is 'intimately familiar' with nasal swabs – the easiest and most common way to test for a positive COVID-19 case.
During her trip to France, Harris will meet with President Emmanuel Macron. attend a peace forum with other world leaders and join commemorations for the anniversary of the end of World War I.
She will also participate in a conference on strengthening Libya's borders.
Upon landing in Paris on Tuesday morning, Harris was asked by a reporter: 'What's your message for President Macron?'
'It is good to be in France and I am looking forward to many many days of productive discussions reinforcing the strength of our relationship,' she dodged, remaining unresponsive with a question on how she will 'ease tensions' with the French president.
Harris' four-day trip to Paris is a charm offensive aimed at Macron after President Joe Biden 's 'clumsy' handling of the row over the new US-British submarine deal with Australia.
During the trip to the research institute, Harris suggested that politics should be more like science when she was asked about rising tensions with Macron.
A French reporter questioned Harris on reconciliation with France following the AUKUS rift, claiming that the institute was showing collaboration between Washington and Paris.
Harris agreed and spoke at length about the scientific process and how it's better than politics because it involves hypothesis and inquiry instead of just presenting a big plan.
'Scientists operate with a hypothesis. I love that. They start out with a hypothesis and they test it out,' she said, adding that if it doesn't work out 'everyone gets together and no one gets beat up about it.'
'With us in government we campaign with the plan – uppercase T uppercase P,' Harris added, claiming there's not much room for innovation and fixes if there are 'glitches.'
She said that was a general statement and not overall comments on Bidne's Build Back Better agenda failing to pass last month in a $3.5 trillion social spending and welfare package in Congress.
'There will be glitches and there will be mistakes,' she said of policy making. 'If you don't make the same mistake twice … that's a good process and we should encourage it.'
Harris touched down aboard Air Force Two with Emhoff, a lawyer, ahead of a meeting with Macron at the Elysee Palace on Wednesday.
There is pressure on the VP to smooth over the cracks after Macron was stunned by Washington's new AUKUS security pact with Australia and Britain in September.
Macron furiously recalled the US ambassador over the snub which saw Australia shred a submarine contract with the French worth AU$90million in favor of a new deal with the US and the UK.
Harris will sit down with Macron to discuss how the two nations can coordinate efforts in the Indo-Pacific, where the Aukus alliance is also focused.
The high-level meeting comes less than two weeks after Biden met Macron on the margins of the Group of 20 summit in Rome and acknowledged that his administration had handled the submarine deal in a 'clumsy' way.
The U.S. and Britain's agreement to provide Australia with submarine technology has been framed as opportunity for the U.S. to bolster a key Pacific ally's naval capacity as the Biden administration has become increasingly concerned about China's military aggressiveness in the region.
But France was livid, saying it was kept in the dark about the deal and its interests were ignored despite having territories in the Indo-Pacific with 2 million people and 7,000 troops.
The French also complained that the episode undercut Biden's message that he would stabilize and strengthen the trans-Atlantic alliance after four years of President Donald Trump's 'America first' approach to foreign policy.
France even briefly withdrew its ambassador from the U.S. in protest, the first time it had done so in some 250 years of diplomatic relations between the nations.
'The alliance between the United States and France is America's oldest, and among our strongest,' Harris said in statement about her trip. 'I look forward to discussing with President Macron our work together on the most urgent challenges of our time - including the climate crisis, the global health crisis, and regional security concerns.'
Harris said she and Macron would also discuss new opportunities for collaboration in the area of space. 
On Tuesday, she is scheduled to tour the renowned Institut Pasteur to meet with American and French scientists working on COVID-19 preparedness worldwide.
Officials said the visit will underscore the longstanding scientific exchanges between the US and France, and the determination to tackle global challenges, especially to to end the pandemic.
But the institute also has a personal symbolism for Harris. Her late mother, who was a scientist, conducted breast cancer research with the institute's scientists in the 1980s.
Harris will deliver a speech on Thursday at the annual Paris Peace Forum and participate the following day in the Paris Conference on Libya.  
The vice president is looking to pick up where Biden left off in Rome in efforts to make clear that that he sees the relationship with France as critical to the U.S.
To that end, she and Emhoff will visit Suresnes American Cemetery and Memorial just outside Paris. The 7.5-acre (3 hectare) cemetery contains the remains of 1,559 Americans who died in World War I and 23 unknown dead of World War II.
Harris will also participate in a ceremony to mark Armistice Day, the French commemoration of the end of World War I. Thursday is also Veterans Day in the United States.